One of the most popular types of medication in history is coming under scrutiny because recent studies have shown a significant increase in the risk of kidney damage related to their use. Nexium and Prilosec are now even available over-the-counter and many people have gotten into a habit of taking them for symptoms of heartburn and indigestion. Click to read full story here.
One aspect of PPIs has largely been flying under the radar, however. Several years ago, Danish researchers discovered that once patients begin taking PPI medications it is nearly impossible for them to stop. The reason has to do with a phenomenon known as “rebound acid hypersecretion.” Essentially, PPIs wind up causing the same symptoms they are intended to treat.
By now, news of the connection between the use of proton pump inhibitors (PPIs) on patients and serious kidney damage has spread widely. Investigation into PPI drugs that include Prilosec andNexium has just begun, although other safety concerns about PPIs (involving the elevated risk of heart attacks and osteoporosis) were first raised over a decade ago.